翻訳と辞書 Words near each other ・ Cytochrophin-4 ・ Cytodeme ・ Cytogenetic and Genome Research ・ Cytogenetic notation ・ Cytogenetics ・ Cytoglobin ・ Cytohet ・ CytoJournal ・ Cytokeratin ・ Cytokine ・ Cytokine adsorbing column ・ Cytokine receptor ・ Cytokine redundancy ・ Cytokine release syndrome ・ Cytokine storm ・ Cytokine-induced killer cell ・ Cytokinesis ・ Cytokinin ・ Cytokinin 7-beta-glucosyltransferase ・ Cytokinin dehydrogenase ・ Cytolethal distending toxin ・ Cytology ・ Cytoluminescent therapy ・ Cytolysin ・ Cytolysis ・ Cytomegalic inclusion body disease ・ Cytomegalovirus ・ Cytomegalovirus colitis ・ Cytomegalovirus esophagitis ・ Cytomegalovirus retinitis Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Cytokine-induced killer cell ： ウィキペディア英語版 Cytokine-induced killer cell Cytokine-induced killer cells or CIK cells are a group of immune effector cells featuring a mixed T- and natural killer (NK) cell-like phenotype. They are generated by ex vivo incubation of human peripheral blood mononuclear cells (PBMC) or cord blood mononuclear cells with interferon-gamma (IFN-γ), anti-CD3 antibody , recombinant human interleukin (IL-) 1 and recombinant human interleukin (IL)-2. Typically, immune cells detect major histocompatibility complex (MHC) presented on infected cell surfaces, triggering cytokine release, causing lysis or apoptosis. However, CIK cells have the ability to recognize infected or even malignant cells in the absence of antibodies and MHC, allowing for a fast and unbiased immune reaction. This is of particular importance as harmful cells that are missing MHC markers cannot be tracked and attacked by other immune cells, such as T-lymphocytes. As a special feature, terminally differentiated CD3+CD56+ CIK cells possess the capacity for both MHC-restricted and MHC-unrestricted anti-tumor cytotoxicity. These properties, inter alia, rendered CIK cells attractive as a potential therapy for cancer and viral infections. == Nomenclature == They were given the name “cytokine-induced killer” because cultivation with certain cytokines is mandatory for the maturation into terminally differentiated CIK cells. Several sources also call them natural killer cell-like T cells due to their close relationship to NK cells. Others propose to classify CIK cells as subset of NKT cells. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Cytokine-induced killer cell」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.